Protein Phosphorylation Antibody Pairs
Cell Signaling Technology PathScanR Phospho-SMAD2 Ser465467 Sandwich ELISA Kit 5 Kit
PathScanR Phospho-SMAD2 Ser465467 Sandwich ELISA Kit 5 Kit
ABclonal Technology Phospho-Smad5-S463/S465 Rabbit pAb
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Cell Signaling Technology PathScanR Phospho-SMAD2 Ser465467SMAD3 Ser423425 Sandwich ELISA Kit 5 Kit
PathScanR Phospho-SMAD2 Ser465467SMAD3 Ser423425 Sandwich ELISA Kit 5 Kit
Medchemexpress LLC Phospho-c-Myc(Ser62) Antibody (YA211) | Predicted band size: 49 kDa; Observed band size: 57 kDa | 50 UL
The Phospho-c-Myc(Ser62) antibody is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Phospho-c-Myc(Ser62). It is suitable for various laboratory research applications, including Western Blot, immunocytochemistry/immunofluorescence, immunohistochemistry-paraffin, and immunoprecipitation.
- Host: rabbit
- Reactivity: human
- Isotype: IgG monoclonal antibody
- Conjugation: non-conjugated
- Applications: WB, ICC/IF, IHC-P, IP
- Formulation: supplied in 1*TBS (pH7.4), 0.05% BSA, 40% glycerol, and 0.05% sodium azide
- Storage: store at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Shipping: shipped with blue ice
ABclonal Technology Phospho-Smad2-S467 Rabbit pAb
This gene encodes a SMAD protein, which mediates signaling in the TGF-beta pathway and regulates processes like cell proliferation, apoptosis, and differentiation. It interacts with the SMAD anchor for receptor activation (SARA) protein and is phosphorylated by TGF-beta receptors. Phosphorylation leads to dissociation from SARA and association with SMAD4, facilitating its nuclear translocation. In the nucleus, it forms a repressor complex with cofactors to regulate gene expression. This protein can also be phosphorylated by the activin type 1 receptor kinase to mediate activin signaling. Alternative splicing produces multiple transcript variants.
Medchemexpress LLC Phospho-c-Myc (Ser62) Antibody (YA212) | 10 UL
Phospho-c-Myc (Ser62) Antibody (YA212) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Phospho-c-Myc (Ser62). It is supplied as a liquid in PBS, pH 7.4, and is affinity purified. This antibody is suitable for use in various applications including Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), and Immunoprecipitation (IP).
- Targets Phospho-c-Myc (Ser62)
- Rabbit-derived monoclonal antibody
- Non-conjugated IgG
- Suitable for WB, ICC/IF, and IP applications
ABclonal Technology p-SMAD1/5/9-S463/S465/S467
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase and may be involved in cancer Alternative splicing results in multiple transcript variants
ABclonal Technology Phospho-Smad2-S245/S250/S255
This gene encodes a protein from the SMAD family which functions as a signal transducer and transcriptional modulator in various signaling pathways It mediates the transforming growth factor (TGF)-beta signal regulating cell proliferation apoptosis and differentiation The protein interacts with the SMAD anchor for receptor activation (SARA) and is phosphorylated by TGF-beta receptors leading to its dissociation from SARA and association with SMAD4 This interaction is crucial for nuclear translocation where the protein binds to target promoters and forms a transcription repressor complex It can also be phosphorylated by activin receptor kinase to mediate activin signals Alternative splicing results in different transcript variants
ABclonal Technology p-Smad2/3-S465/S467/S423/S425
The protein encoded by this gene belongs to the SMAD family which includes proteins similar to Drosophila Mad and C elegans Sma SMAD proteins are signal transducers and transcriptional modulators involved in multiple signaling pathways This protein mediates the transforming growth factor (TGF)-beta signal regulating cell processes like proliferation apoptosis and differentiation It is recruited to TGF-beta receptors via its interaction with the SMAD anchor for receptor activation (SARA) protein Phosphorylation by TGF-beta receptors causes dissociation from SARA and association with SMAD4 which is essential for nuclear translocation In the nucleus it binds to target promoters and forms a transcription repressor complex The protein can also be phosphorylated by activin type 1 receptor kinase mediating activin signaling Alternative splicing results in multiple transcript variants
ABclonal Technology Phospho-Smad2-S245/S250/S255
This gene encodes a protein from the SMAD family which functions as a signal transducer and transcriptional modulator in various signaling pathways It mediates the transforming growth factor (TGF)-beta signal regulating cell proliferation apoptosis and differentiation The protein interacts with the SMAD anchor for receptor activation (SARA) and is phosphorylated by TGF-beta receptors leading to its dissociation from SARA and association with SMAD4 This interaction is crucial for nuclear translocation where the protein binds to target promoters and forms a transcription repressor complex It can also be phosphorylated by activin receptor kinase to mediate activin signals Alternative splicing results in different transcript variants
ABclonal Technology Phospho-Smad2-S465/S467
This gene encodes a protein from the SMAD family which functions as a signal transducer and transcriptional modulator in various signaling pathways It mediates the transforming growth factor (TGF)-beta signal regulating cell proliferation apoptosis and differentiation The protein interacts with the SMAD anchor for receptor activation (SARA) and is phosphorylated by TGF-beta receptors leading to its dissociation from SARA and association with SMAD4 This interaction is crucial for nuclear translocation where the protein binds to target promoters and forms a transcription repressor complex It can also be phosphorylated by activin receptor kinase to mediate activin signals Alternative splicing results in different transcript variants
ABclonal Technology Phospho-NF-B p105-S932
This gene encodes a 105 kD protein that is processed by the 26S proteasome into a 50 kD protein The 105 kD protein acts as a Rel protein-specific transcription inhibitor while the 50 kD protein is a DNA-binding subunit of the NF-kappa-B (NFKB) complex NFKB activated by stimuli like cytokines UV irradiation and bacterial or viral products regulates various biological functions Once activated NFKB translocates to the nucleus to stimulate gene expression Inappropriate NFKB activation is linked to inflammatory diseases while its inhibition can disrupt immune cell development and delay cell growth NFKB also regulates the early response to viral infections Alternative splicing generates multiple isoforms including proteolytically processed variants